BDBM8056 2-Anilino-4-(thiazol-5-yl)pyrimidine deriv. 27::4-(2,4-dimethyl-1,3-thiazol-5-yl)-N-(3-nitrophenyl)pyrimidin-2-amine

SMILES Cc1nc(C)c(s1)-c1ccnc(Nc2cccc(c2)N(=O)=O)n1

InChI Key InChIKey=DEIGLICSSNUYPO-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 8056   

LigandPNGBDBM8056(4-(2,4-dimethyl-1,3-thiazol-5-yl)-N-(3-nitrophenyl...)
Affinity DataKi:  110nM ΔG°:  -9.65kcal/moleT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 100 uM ATP/ [gamma-32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2006
Entry Details Article
PubMed
LigandPNGBDBM8056(4-(2,4-dimethyl-1,3-thiazol-5-yl)-N-(3-nitrophenyl...)
Affinity DataKi: >2.00E+4nM ΔG°: >-6.51kcal/moleT: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of 100 uM ATP/ [gamma-32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/13/2006
Entry Details Article
PubMed