BDBM802636 (S)-1-(5-((4-chloro-2-methyl-2H- indazol-5-yl)thio)pyrazin- 2-yl)-4'H,6'H-spiro[piperidine-4,5'- pyrrolo[1,2-b]pyrazol]-4'- amine::US20260109699, Example 84

SMILES Cn1cc2c(Cl)c(Sc3cnc(N4CCC5(CC4)Cn4nccc4[C@H]5N)cn3)ccc2n1

InChI Key InChIKey=NMLAPINHVKYLLP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 802636   

LigandChemical structure of BindingDB Monomer ID 802636BDBM802636((S)-1-(5-((4-chloro-2-methyl-2H- indazol-5-yl)thio...)
Affinity DataIC50: 50nMAssay Description:A panel of four LanthaScreen JAK biochemical assays (JAK1, 2, 3 and Tyk2) were carried in a common kinase reaction buffer (50 mM HEPES, pH 7.5, 0.01%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
9/3/2026
Entry Details
US Patent