BDBM79172 2-[4-[(3Z)-3-[2-(trifluoromethyl)-9-thioxanthenylidene]propyl]-1-piperazinyl]ethanol;hydrochloride::2-[4-[(3Z)-3-[2-(trifluoromethyl)thioxanthen-9-ylidene]propyl]piperazin-1-yl]ethanol;hydrochloride::2-[4-[(3Z)-3-[2-(trifluoromethyl)thioxanthen-9-ylidene]propyl]piperazino]ethanol;hydrochloride::Fluphenthixol::MLS001332581::SMR000875208::cid_10140115::cis-(Z)-Flupenthixol dihydrochloride

SMILES OCCN1CCN(CC\C=C2\c3ccccc3Sc3ccc(cc23)C(F)(F)F)CC1

InChI Key InChIKey=NJMYODHXAKYRHW-UHFFFAOYSA-N

Data  2 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 79172   

TargetD(2) dopamine receptor(Rat)
University of North Texas

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 79172BDBM79172(Fluphenthixol | SMR000875208 | cid_10140115 | 2-[4...)
Affinity DataKi:  0.25nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2012
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
Yale University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 79172BDBM79172(Fluphenthixol | SMR000875208 | cid_10140115 | 2-[4...)
Affinity DataIC50: 0.300nMAssay Description:In vivo binding affinity against dopamine (D1) receptor in rat caudate-putamen tissue using [3H]SCH-23390 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of North Carolina

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 79172BDBM79172(Fluphenthixol | SMR000875208 | cid_10140115 | 2-[4...)
Affinity DataIC50: 2.20nMAssay Description:The compound was tested for affinity towards sigma-3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 79172BDBM79172(Fluphenthixol | SMR000875208 | cid_10140115 | 2-[4...)
Affinity DataIC50: 3nMAssay Description:Ability to displace [3H]haloperidol from rat striatal membranes, in order to measure its intrinsic affinity for the dopamine (DA) receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Sri International

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 79172BDBM79172(Fluphenthixol | SMR000875208 | cid_10140115 | 2-[4...)
Affinity DataKi:  13nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMed
TargetPotassium channel subfamily K member 2(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 79172BDBM79172(Fluphenthixol | SMR000875208 | cid_10140115 | 2-[4...)
Affinity DataIC50: 1.80E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2026
Entry Details PubMed
TargetPotassium channel subfamily K member 2(Human)
Chinese Academy of Medical Sciences and Peking Union Medical College

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 79172BDBM79172(Fluphenthixol | SMR000875208 | cid_10140115 | 2-[4...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of of human TREK1 expressed in whole COS cells assessed as reduction in channel currentsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2017
Entry Details Article
PubMed
TargetWD repeat-containing protein 48(Human)
University of Connecticut Health Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 79172BDBM79172(Fluphenthixol | SMR000875208 | cid_10140115 | 2-[4...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human USP1/UAF1 complex using Ub-Rho as substrate by qHTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2018
Entry Details Article
PubMed
TargetUbiquitin-conjugating enzyme E2 N(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 79172BDBM79172(Fluphenthixol | SMR000875208 | cid_10140115 | 2-[4...)
Affinity DataIC50: 2.00E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego CA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2011
Entry Details
PCBioAssay