BDBM7869 2-chloro-1-(4,5-dibromothiophen-2-yl)ethan-1-one::Chloromethyl Thienyl Ketone deriv. 17

SMILES ClCC(=O)c1cc(Br)c(Br)s1

InChI Key InChIKey=KYVDGDMQERQKOY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 7869   

TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Instituto De Quimica Medica (Csic)

LigandPNGBDBM7869(2-chloro-1-(4,5-dibromothiophen-2-yl)ethan-1-one |...)
Affinity DataIC50: 1.00E+3nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Instituto De Qu£Mica M£Dica-Csic

Curated by ChEMBL
LigandPNGBDBM7869(2-chloro-1-(4,5-dibromothiophen-2-yl)ethan-1-one |...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of GSK3-beta by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Instituto De Qu£Mica M£Dica-Csic

Curated by ChEMBL
LigandPNGBDBM7869(2-chloro-1-(4,5-dibromothiophen-2-yl)ethan-1-one |...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of GSK3-betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/1/2013
Entry Details Article
PubMed