BDBM7857 1-(2-bromo-4,5-dichlorothiophen-3-yl)-2-chloroethan-1-one::Chloromethyl Thienyl Ketone deriv. 5

SMILES ClCC(=O)c1c(Cl)c(Cl)sc1Br

InChI Key InChIKey=MMPGUTMCAGDIPN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 7857   

TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Instituto De Quimica Medica (Csic)

LigandPNGBDBM7857(1-(2-bromo-4,5-dichlorothiophen-3-yl)-2-chloroetha...)
Affinity DataIC50: 2.00E+3nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Instituto De Qu£Mica M£Dica-Csic

Curated by ChEMBL
LigandPNGBDBM7857(1-(2-bromo-4,5-dichlorothiophen-3-yl)-2-chloroetha...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of GSK3-beta by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed