BDBM7853 2-chloro-1-(4,5-dichlorothiophen-2-yl)ethan-1-one::Chloromethyl Thienyl Ketone deriv. 1

SMILES ClCC(=O)c1cc(Cl)c(Cl)s1

InChI Key InChIKey=OUAXIWPMWPAZMA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 7853   

TargetGlycogen synthase kinase-3 beta [7-25](Rabbit)
Instituto De Quimica Medica (Csic)

LigandPNGBDBM7853(2-chloro-1-(4,5-dichlorothiophen-2-yl)ethan-1-one ...)
Affinity DataIC50: 2.50E+3nMpH: 7.5 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 37 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Instituto De Qu£Mica M£Dica-Csic

Curated by ChEMBL
LigandPNGBDBM7853(2-chloro-1-(4,5-dichlorothiophen-2-yl)ethan-1-one ...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of GSK3-beta by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Instituto De Qu£Mica M£Dica-Csic

Curated by ChEMBL
LigandPNGBDBM7853(2-chloro-1-(4,5-dichlorothiophen-2-yl)ethan-1-one ...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of GSK-3beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed