BDBM784854 (1S,3R,5R)-N-(4-chloro-3-cyclobutylphenyl)-1-(5-methyl-1,3,4-oxadiazol-2-yl)-3-(trifluoromethyl)-6-azabicyclo[3.1.1]heptane-6-carboxamide::WO2025054369, Example 68

SMILES Cc1nnc([C@@]23C[C@@H](C[C@@H](C(F)(F)F)C2)N3C(=O)Nc2ccc(Cl)c(C3CCC3)c2)o1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 784854   

TargetNAD(+) hydrolase SARM1(Human)
NICO Therapeutics

WIPO
LigandChemical structure of BindingDB Monomer ID 784854BDBM784854((1S,3R,5R)-N-(4-chloro-3-cyclobutylphenyl)-1-(5-me...)
Affinity DataIC50: 1.00E+3nMAssay Description:Preparation of full-length SARM1 (FL-SARM1) lysate: HEK293T cells (ATCC: CRL-3216) were grown on 150 mm TC-treated dishes to 80-90% confluency in com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/26/2026
Entry Details
WIPO WO2025054369