BDBM784699 5-[4-(8,8-difluoro-6-azaspiro[3.4]octan-6-yl)-7-fluoro-pyrazolo[4,3-c]pyridin-2-yl]-1H-pyrimidine-2,4-dione::US20250340565, Example 26.1

SMILES O=c1[nH]cc(-n2cc3c(N4CC(F)(F)C5(CCC5)C4)ncc(F)c3n2)c(=O)[nH]1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 784699   

Target5'-nucleotidase [27-547](Human)
AdoRx Therapeutics

US Patent
LigandPNGBDBM784699(5-[4-(8,8-difluoro-6-azaspiro[3.4]octan-6-yl)-7-fl...)
Affinity DataIC50: 22.9nMAssay Description:Compound inhibition of human (h)CD73 (amino acids Trp27-Lys547, R&D Systems 5795-EN-500) enzymatic activity was tested via the Malachite Green Phosph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/25/2026
Entry Details
US Patent