BDBM784648 5-[4-[3-[2-(1-Piperidyl)ethoxy]pyrrolidin-1-yl]thieno[3,2-d]pyrimidin-6-yl]-1H-pyrimidine-2,4-dione::US20250340565, Example 8

SMILES O=c1[nH]cc(-c2cc3ncnc(N4CCC(OCCN5CCCCC5)C4)c3s2)c(=O)[nH]1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 784648   

Target5'-nucleotidase [27-547](Human)
AdoRx Therapeutics

US Patent
LigandPNGBDBM784648(5-[4-[3-[2-(1-Piperidyl)ethoxy]pyrrolidin-1-yl]thi...)
Affinity DataIC50: 20.1nMAssay Description:Compound inhibition of human (h)CD73 (amino acids Trp27-Lys547, R&D Systems 5795-EN-500) enzymatic activity was tested via the Malachite Green Phosph...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/25/2026
Entry Details
US Patent