BDBM784618 US20250340556, Compound SLT-042

SMILES Cc1cccc(C)c1N1Cc2cnc3nc2N(CCCCOC(=O)c2cc(ccc2N2CCN(C)CC2)N3)C1=O

InChI Key

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 784618   

TargetSerine/threonine-protein kinase SIK2(Human)
Soltego

US Patent
LigandPNGBDBM784618(US20250340556, Compound SLT-042)
Affinity DataIC50: 0.700nMAssay Description:SIK (h) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM AMARAASAAALARRR, 10 mM Magnesium acetate and [γ-33P]-ATP (specific activity and conc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/25/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK3(Human)
Soltego

US Patent
LigandPNGBDBM784618(US20250340556, Compound SLT-042)
Affinity DataIC50: 2nMAssay Description:SIK (h) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM AMARAASAAALARRR, 10 mM Magnesium acetate and [γ-33P]-ATP (specific activity and conc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/25/2026
Entry Details
US Patent

TargetSerine/threonine-protein kinase SIK1(Human)
Soltego

US Patent
LigandPNGBDBM784618(US20250340556, Compound SLT-042)
Affinity DataIC50: 2nMAssay Description:SIK (h) was incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 100 μM AMARAASAAALARRR, 10 mM Magnesium acetate and [γ-33P]-ATP (specific activity and conc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/25/2026
Entry Details
US Patent