BDBM783361 (2S,2''S)-N,N''-(1,4- phenylenebis(methylene)) bis(4-(((2R,5R)-1- (2-(6-(4-chloro-2- methoxybenzyl)-3,3- dimethyl-5-oxo- 2,3,4,5-tetrahydro-1H- pyrrolo[3,2-b]pyridin- 1-yl)-2-oxoethyl)-5- methylpiperazin-2- yl)methyl)morpholine- 2-carboxamide)::US20250326771, Compound 169

SMILES COc1cc(Cl)ccc1Cc1cc2c([nH]c1=O)C(C)(C)CN2C(=O)CN1C[C@@H](C)NC[C@@H]1CN1CCO[C@H](C(=O)NCc2ccc(CNC(=O)[C@@H]3CN(C[C@H]4CN[C@H](C)CN4CC(=O)N4CC(C)(C)c5[nH]c(=O)c(Cc6ccc(Cl)cc6OC)cc54)CCO3)cc2)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 783361   

TargetBaculoviral IAP repeat-containing protein 3 [255-322](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783361((2S,2'S)-N,N'-(1,4- phenylenebis(methylene)) bis(4...)
Affinity DataIC50: 5.35nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/11/2026
Entry Details US Patent

TargetBaculoviral IAP repeat-containing protein 2 [269-336](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783361((2S,2'S)-N,N'-(1,4- phenylenebis(methylene)) bis(4...)
Affinity DataIC50: 15.8nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/11/2026
Entry Details US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783361((2S,2'S)-N,N'-(1,4- phenylenebis(methylene)) bis(4...)
Affinity DataIC50: 282nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/11/2026
Entry Details US Patent