BDBM783359 (2S,2''S)-N,N''-(1,4- phenylenebis(methylene)) bis(4-(((2R,5R)-1- (2-(3,3-dimethyl-5- oxo-6-(2,4,6- trifluorobenzyl)- 2,3,4,5-tetrahydro-1H- pyrrolo[3,2-b]pyridin- 1-yl)-2-oxoethyl)-5- methylpiperazin-2- yl)methyl)morpholine- 2-carboxamide)::US20250326771, Compound 167

SMILES C[C@@H]1CN(CC(=O)N2CC(C)(C)c3[nH]c(=O)c(Cc4c(F)cc(F)cc4F)cc32)[C@@H](CN2CCO[C@H](C(=O)NCc3ccc(CNC(=O)[C@@H]4CN(C[C@H]5CN[C@H](C)CN5CC(=O)N5CC(C)(C)c6[nH]c(=O)c(Cc7c(F)cc(F)cc7F)cc65)CCO4)cc3)C2)CN1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 783359   

TargetBaculoviral IAP repeat-containing protein 3 [255-322](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783359((2S,2'S)-N,N'-(1,4- phenylenebis(methylene)) bis(4...)
Affinity DataIC50: 5.35nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/11/2026
Entry Details US Patent

TargetBaculoviral IAP repeat-containing protein 2 [269-336](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783359((2S,2'S)-N,N'-(1,4- phenylenebis(methylene)) bis(4...)
Affinity DataIC50: 15.8nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/11/2026
Entry Details US Patent

TargetE3 ubiquitin-protein ligase XIAP [265-330](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783359((2S,2'S)-N,N'-(1,4- phenylenebis(methylene)) bis(4...)
Affinity DataIC50: 31.6nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/11/2026
Entry Details US Patent

TargetBaculoviral IAP repeat-containing protein 3 [169-235](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783359((2S,2'S)-N,N'-(1,4- phenylenebis(methylene)) bis(4...)
Affinity DataIC50: 522nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/11/2026
Entry Details US Patent

TargetBaculoviral IAP repeat-containing protein 2 [184-250](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783359((2S,2'S)-N,N'-(1,4- phenylenebis(methylene)) bis(4...)
Affinity DataIC50: 522nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/11/2026
Entry Details US Patent

TargetE3 ubiquitin-protein ligase XIAP [163-230](Human)
Viiv Healthcare

US Patent
LigandPNGBDBM783359((2S,2'S)-N,N'-(1,4- phenylenebis(methylene)) bis(4...)
Affinity DataIC50: 3.57E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
2/11/2026
Entry Details US Patent