BDBM782612 US20250325552, Compound 195

SMILES COc1cccc(F)c1-c1cc2cnc(C)n2cc1C(=O)Nc1nnc(OC[C@H]2CC[C@H](O)CC2)s1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 782612   

TargetDNA polymerase theta [1-899](Human)
Ideaya Biosciences

US Patent
LigandPNGBDBM782612(US20250325552, Compound 195)
Affinity DataIC50: 50nMAssay Description:Polθ Theta ATPase activity was determined by measuring the rate of ATP turn over in a NADH oxidation-coupled enzymatic assay. 10-point dilution serie...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/11/2026
Entry Details
US Patent