BDBM78179 2-(2-propyl-4-pyridyl)-4-(p-tolyl)thiazole;hydrobromide::2-Propyl-4-(4-p-tolyl-thiazol-2-yl)-pyridine::4-(4-methylphenyl)-2-(2-propyl-4-pyridinyl)thiazole;hydrobromide::4-(4-methylphenyl)-2-(2-propylpyridin-4-yl)-1,3-thiazole;hydrobromide::CHEMBL1621019::MLS000332366::SMR000221636::cid_2850562

SMILES CCCc1cc(ccn1)-c1nc(cs1)-c1ccc(C)cc1

InChI Key InChIKey=ZROSUBKIGBSZCG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 78179   

TargetMitochondrial import inner membrane translocase subunit TIM10(Baker's yeast)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM78179(SMR000221636 | CHEMBL1621019 | 4-(4-methylphenyl)-...)
Affinity DataIC50: 4.97E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, CA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/2/2011
Entry Details
PCBioAssay
TargetSterol regulatory element-binding protein 2(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM78179(SMR000221636 | CHEMBL1621019 | 4-(4-methylphenyl)-...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells co-transfected with pSRE-Luc plasmid assessed as inhibition of luciferase expression after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSterol regulatory element-binding protein 2(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM78179(SMR000221636 | CHEMBL1621019 | 4-(4-methylphenyl)-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SREBP2 activation expressed in CHO-K1 cells by densitometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed