BDBM777378 US12441708, Example 32::US20250313547, Example 32

SMILES O=C1CCN(c2cncc3ccccc23)C(=O)N1

InChI Key

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 777378   

TargetProtein cereblon(Human)
Arvinas Operations

US Patent
LigandPNGBDBM777378(US20250313547, Example 32 | US12441708, Example 32)
Affinity DataKd:  5.50E+3nMAssay Description:The surface plasmon resonance (SPR) experiments were conducted on a Biacore3000 (GE Healthcare). Myc-tagged cereblon was immobilized on a carboxymeth...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/4/2026
Entry Details
US Patent

TargetProtein cereblon(Human)
Arvinas Operations

US Patent
LigandPNGBDBM777378(US20250313547, Example 32 | US12441708, Example 32)
Affinity DataKd:  5.50E+3nMAssay Description:The surface plasmon resonance (SPR) experiments were conducted on a Biacore3000 (GE Healthcare). Myc-tagged cereblon was immobilized on a carboxymeth...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent