BDBM777373 US12441708, Example 27::US20250313547, Example 27

SMILES Cc1c(N2CCC(=O)NC2=O)cnc2ccccc12

InChI Key

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 777373   

TargetProtein cereblon(Human)
Arvinas Operations

US Patent
LigandPNGBDBM777373(US20250313547, Example 27 | US12441708, Example 27)
Affinity DataKd: >1.00E+5nMAssay Description:The surface plasmon resonance (SPR) experiments were conducted on a Biacore3000 (GE Healthcare). Myc-tagged cereblon was immobilized on a carboxymeth...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent

TargetProtein cereblon(Human)
Arvinas Operations

US Patent
LigandPNGBDBM777373(US20250313547, Example 27 | US12441708, Example 27)
Affinity DataKd: >1.00E+5nMAssay Description:The surface plasmon resonance (SPR) experiments were conducted on a Biacore3000 (GE Healthcare). Myc-tagged cereblon was immobilized on a carboxymeth...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
2/4/2026
Entry Details
US Patent