BDBM776810 US20250313535, Compound 519

SMILES CC(=O)CN1CCC(C(=O)N[C@@H](Cc2cccc3c(-c4c(C(F)(F)F)c5ccccc5n(C)c4=O)cccc23)C(=O)O)(C(F)(F)F)CC1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 776810   

TargetIntegrin alpha-4/beta-7(Human)
Dice Molecules Sv

US Patent
LigandChemical structure of BindingDB Monomer ID 776810BDBM776810(US20250313535, Compound 519)
Affinity DataIC50: 10nMAssay Description:MAdCAM (R&D Systems, 0.1 ug) was diluted in 50 μL PBS, added to each well of an opaque ELISA plate (Thermo), and incubated overnight at 4° C. Coated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent

TargetIntegrin alpha-4/beta-1(Human)
Dice Molecules Sv

US Patent
LigandChemical structure of BindingDB Monomer ID 776810BDBM776810(US20250313535, Compound 519)
Affinity DataIC50: 100nMAssay Description:MAdCAM (R&D Systems, 0.1 ug) was diluted in 50 μL PBS, added to each well of an opaque ELISA plate (Thermo), and incubated overnight at 4° C. Coated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
1/26/2026
Entry Details
US Patent