BDBM775592 US12435089, Example 71

SMILES COc1ccc(F)cc1[C@@H](C)Oc1ccn2ncc(C3=NOC(C)(C)N3)c2n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 775592   

TargetProto-oncogene tyrosine-protein kinase ROS (G2032R)(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775592(US12435089, Example 71)
Affinity DataIC50: 2.75nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent

TargetProto-oncogene tyrosine-protein kinase ROS(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775592(US12435089, Example 71)
Affinity DataIC50: 2.75nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor [G595R](Human)
Tyk Medicines

US Patent
LigandPNGBDBM775592(US12435089, Example 71)
Affinity DataIC50: 2.75nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775592(US12435089, Example 71)
Affinity DataIC50: 2.75nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent

TargetNT-3 growth factor receptor(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775592(US12435089, Example 71)
Affinity DataIC50: 2.75nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent

TargetBDNF/NT-3 growth factors receptor(Human)
Tyk Medicines

US Patent
LigandPNGBDBM775592(US12435089, Example 71)
Affinity DataIC50: 2.75nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/22/2026
Entry Details
US Patent