BDBM77537 5-({4-bromo-3-nitro-1H-pyrazol-1-yl}methyl)-N'-(3-chlorobenzylidene)-2-furohydrazide::5-[(4-bromanyl-3-nitro-pyrazol-1-yl)methyl]-N-[(3-chlorophenyl)methylideneamino]furan-2-carboxamide::5-[(4-bromo-3-nitro-1-pyrazolyl)methyl]-N-[(3-chlorophenyl)methylideneamino]-2-furancarboxamide::5-[(4-bromo-3-nitro-pyrazol-1-yl)methyl]-N-[(3-chlorobenzylidene)amino]-2-furamide::5-[(4-bromo-3-nitropyrazol-1-yl)methyl]-N-[(3-chlorophenyl)methylideneamino]furan-2-carboxamide::MLS000699328::SMR000227717::cid_1757402

SMILES C[C@]12CC/C(=C\CC3CCNCC3)CC1[C@@H](O)C[C@@H]1[C@@H]2CC[C@]2(C)C(=O)CC[C@@H]12

InChI Key InChIKey=DQXWDPYRUBCXJN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 77537   

TargetSodium/potassium-transporting ATPase subunit alpha-1(Dog)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 77537BDBM77537((E)-3-[2-(piperidin-4-yl)ethyliden]-6alpha-hydroxy...)
Affinity DataIC50: 1.31E+4nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2026
Entry Details
US Patent