BDBM77525 2-(4-bromanyl-5-methyl-3-nitro-pyrazol-1-yl)-N-(furan-2-ylmethyl)propanamide::2-(4-bromo-5-methyl-3-nitro-1-pyrazolyl)-N-(2-furanylmethyl)propanamide::2-(4-bromo-5-methyl-3-nitro-1H-pyrazol-1-yl)-N-(2-furylmethyl)propanamide::2-(4-bromo-5-methyl-3-nitro-pyrazol-1-yl)-N-(2-furfuryl)propionamide::2-(4-bromo-5-methyl-3-nitropyrazol-1-yl)-N-(furan-2-ylmethyl)propanamide::MLS000582950::SMR000201659::cid_2984161

SMILES O=C(NCCC[C@@H](Cc1ccccc1)C(=O)N1CCC(O)(Cn2cnc3c(N4CCOCC4)cccc3c2=O)CC1)c1ccc2c(Cl)c3c(nc2c1)CCCC3

InChI Key InChIKey=ZALYCIUORLZMBL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 77525   

TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 77525BDBM77525(US12503453, Compound Table3.21 | US12503453, Compo...)
Affinity DataIC50: 60nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2026
Entry Details
US Patent