BDBM77523 Furan-2-carboxylic acid {2,2,2-trichloro-1-[3-(4-chloro-phenyl)-thioureido]-ethyl}-amide::MLS000557161::N-[2,2,2-trichloro-1-[(4-chlorophenyl)carbamothioylamino]ethyl]furan-2-carboxamide::N-[2,2,2-trichloro-1-[(4-chlorophenyl)thiocarbamoylamino]ethyl]-2-furamide::N-[2,2,2-trichloro-1-[[(4-chloroanilino)-sulfanylidenemethyl]amino]ethyl]-2-furancarboxamide::N-[2,2,2-tris(chloranyl)-1-[(4-chlorophenyl)carbamothioylamino]ethyl]furan-2-carboxamide::SMR000173937::cid_2828945

SMILES O=C(CCN1CCOCC1)Nc1ccc2c(=O)n(CC3(O)CCN(C(=O)C(CCCNC(=O)c4ccc5c(Cl)c6c(nc5c4)CCCC6)Cc4ccc(F)cc4F)CC3)cnc2c1

InChI Key InChIKey=WPKZMUWXAYFWJL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 77523   

TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandChemical structure of BindingDB Monomer ID 77523BDBM77523(US12503453, Compound Table3.19 | US12503453, Compo...)
Affinity DataIC50: 60nMAssay Description:Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/4/2026
Entry Details
US Patent