BDBM771842 25-chloro-17,19-difluoro-22,22-dioxo-9-oxa-2λ6-thia-3,4,6,21-tetrazapentacyclo[21.3.1.116,20.02,6.010,15]octacosa-1(26),2,4,10,12,14,16(28),17,19,23(27),24-undecaen-24-ol ::US20250289793, Compound 77

SMILES O=S1(=O)Nc2cc(c(F)cc2F)-c2ccccc2OCCn2cnnc2-c2cc(Cl)c(O)c1c2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 771842   

TargetATP-citrate synthase(Human)
Esperion Therapeutics

US Patent
LigandPNGBDBM771842(25-chloro-17,19-difluoro-22,22-dioxo-9-oxa-2λ6-thi...)
Affinity DataIC50: 20nMAssay Description:Table 2: Compounds of the disclosure were evaluated for their efficacy in inhibiting hACLY using rapid fire mass spectrometry (RF/MS). The final reac...More data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
1/2/2026
Entry Details
US Patent