BDBM771650 Methyl ((1R,3R)-3- (7-(4- ((dimethylamino)meth- yl)phenyl)-8-(4- fluorophenyl)-3- methyl-2-oxo-3,6- dihydroimidazo[4,5- d]pyrrolo[2,3- b]pyridin-1(2H)- yl)cyclopentyl)carba- mate::US20250092044, Example 28

SMILES COC(=O)N[C@@H]1CC[C@@H](n2c(=O)n(C)c3cnc4[nH]c(-c5ccc(CN(C)C)cc5)c(-c5ccc(F)cc5)c4c32)C1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 771650   

LigandPNGBDBM771650(Methyl ((1R,3R)-3- (7-(4- ((dimethylamino)meth- yl...)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Incyte

US Patent
LigandPNGBDBM771650(Methyl ((1R,3R)-3- (7-(4- ((dimethylamino)meth- yl...)
Affinity DataIC50: 750nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Incyte

US Patent
LigandPNGBDBM771650(Methyl ((1R,3R)-3- (7-(4- ((dimethylamino)meth- yl...)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Incyte

US Patent
LigandPNGBDBM771650(Methyl ((1R,3R)-3- (7-(4- ((dimethylamino)meth- yl...)
Affinity DataIC50: 2.50E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent