BDBM771647 US20250092044, Example 25

SMILES [2H]C([2H])([2H])N(Cc7ccc(c2[nH]c1ncc6c(c1c2c4ccc3OC(C)(C)Cc3c4)n([C@@H]5CC[C@@H](NC(=O)OC)C5)c(=O)n6C([2H])([2H])[2H])cc7)C([2H])([2H])[2H]

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 771647   

LigandPNGBDBM771647(US20250092044, Example 25)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Incyte

US Patent
LigandPNGBDBM771647(US20250092044, Example 25)
Affinity DataIC50: 750nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Incyte

US Patent
LigandPNGBDBM771647(US20250092044, Example 25)
Affinity DataIC50: 750nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Incyte

US Patent
LigandPNGBDBM771647(US20250092044, Example 25)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent