BDBM771643 US20250092044, Example 21

SMILES CNC(=O)c1ccc(-c2[nH]c3ncc4c(c3c2-c2ccc3c(cnn3C(C)C)c2)n([C@@H]2CC[C@@H](NC(=O)OC)C2)c(=O)n4C)cc1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 771643   

LigandPNGBDBM771643(US20250092044, Example 21)
Affinity DataIC50: 10nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Incyte

US Patent
LigandPNGBDBM771643(US20250092044, Example 21)
Affinity DataIC50: 750nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetTyrosine-protein kinase JAK2 [826-1132](Human)
Incyte

US Patent
LigandPNGBDBM771643(US20250092044, Example 21)
Affinity DataIC50: 1.00E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent

TargetHigh affinity nerve growth factor receptor(Human)
Incyte

US Patent
LigandPNGBDBM771643(US20250092044, Example 21)
Affinity DataIC50: 1.88E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
TBA
Entry Details
US Patent