BDBM766934 N-(1-cyclopropyl-2-oxo-1,2-dihydropyridin-3-yl)-6-isopropoxy-2-((1S,4S)-1-(methoxymethyl)-2-oxabicyclo[2.2.1]heptan-4-yl)-2H-pyrazolo[3,4-b]pyridine-5-carboxamide and N-(1-cyclopropyl-2-oxo-1,2-dihydropyridin-3-yl)-6-isopropoxy-2-((1R,4R)-1-(methoxymethyl)-2-oxabicyclo[2.2.1]heptan-4-yl)-2H-pyrazolo[3,4-b]pyridine-5-carboxamide::US20250268877, Example 30

SMILES COC[C@@]12CC[C@@](n3cc4cc(C(=O)Nc5cccn(C6CC6)c5=O)c(OC(C)C)nc4n3)(CO1)C2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 766934   

LigandPNGBDBM766934(N-(1-cyclopropyl-2-oxo-1,2-dihydropyridin-3-yl)-6-...)
Affinity DataIC50: 200nMAssay Description:IRAK4 protein. N-terminal His-TEV-AVI tagged catalytical domain of human IRAK4 (a.a. 163-460) was co-expressed with Bir A in insect cells, and purifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
12/8/2025
Entry Details
US Patent