BDBM766931 6-cyclobutoxy-N-(1-((1R,2S)-2-fluorocyclopropyl)-2-oxo-1,2-dihydropyridin-3-yl)-2-(1-methyl-2-oxabicyclo[2.1.1]hexan-4-yl)-2H-pyrazolo[3,4-b]pyridine-5-carboxamide and 6-cyclobutoxy-N-(1-((1S,2R)-2-fluorocyclopropyl)-2-oxo-1,2-dihydropyridin-3-yl)-2-(1-methyl-2-oxabicyclo[2.1.1]hexan-4-yl)-2H-pyrazolo[3,4-b]pyridine-5-carboxamide::US20250268877, Example 27

SMILES CC12CC(n3cc4cc(C(=O)Nc5cccn([C@H]6C[C@H]6F)c5=O)c(OC5CCC5)nc4n3)(CO1)C2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 766931   

LigandPNGBDBM766931(6-cyclobutoxy-N-(1-((1R,2S)-2-fluorocyclopropyl)-2...)
Affinity DataIC50: 100nMAssay Description:IRAK4 protein. N-terminal His-TEV-AVI tagged catalytical domain of human IRAK4 (a.a. 163-460) was co-expressed with Bir A in insect cells, and purifi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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Date in BDB:
12/8/2025
Entry Details
US Patent