BDBM76662 4-methyl-7-phenylmethoxy-1-benzopyran-2-one::4-methyl-7-phenylmethoxy-chromen-2-one::4-methyl-7-phenylmethoxychromen-2-one::7-Benzyloxy-4-methyl-chromen-2-one::7-benzoxy-4-methyl-coumarin::MLS001212241::SMR000514539::cid_728520

SMILES Cc1cc(=O)oc2cc(OCc3ccccc3)ccc12

InChI Key InChIKey=RTORNQDWFDEDPT-UHFFFAOYSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 76662   

TargetCaspase-3(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM76662(7-Benzyloxy-4-methyl-chromen-2-one | 4-methyl-7-ph...)
Affinity DataIC50: 1.65E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2011
Entry Details
PCBioAssay
TargetSentrin-specific protease 8(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM76662(7-Benzyloxy-4-methyl-chromen-2-one | 4-methyl-7-ph...)
Affinity DataIC50: 2.10E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2011
Entry Details
PCBioAssay
TargetSentrin-specific protease 6(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM76662(7-Benzyloxy-4-methyl-chromen-2-one | 4-methyl-7-ph...)
Affinity DataIC50: 2.41E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2011
Entry Details
PCBioAssay
TargetAmine oxidase [flavin-containing] A(Rat)
University of Lausanne

Curated by ChEMBL
LigandPNGBDBM76662(7-Benzyloxy-4-methyl-chromen-2-one | 4-methyl-7-ph...)
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibitory activity against monoamine oxidase AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
University of Lausanne

Curated by ChEMBL
LigandPNGBDBM76662(7-Benzyloxy-4-methyl-chromen-2-one | 4-methyl-7-ph...)
Affinity DataIC50: 18nMAssay Description:Inhibitory activity against monoamine oxidase BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/22/2013
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Rat)
University of Lausanne

Curated by ChEMBL
LigandPNGBDBM76662(7-Benzyloxy-4-methyl-chromen-2-one | 4-methyl-7-ph...)
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibitory effect on monoamine oxidase A, SD on IC50 values < 10%More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
University of Lausanne

Curated by ChEMBL
LigandPNGBDBM76662(7-Benzyloxy-4-methyl-chromen-2-one | 4-methyl-7-ph...)
Affinity DataIC50: 18.2nMAssay Description:Inhibitory effect on Monoamine oxidase B, SD on IC50 values < 10%More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Geneva

Curated by ChEMBL
LigandPNGBDBM76662(7-Benzyloxy-4-methyl-chromen-2-one | 4-methyl-7-ph...)
Affinity DataIC50: 1.58nMAssay Description:Inhibition of human supersomes MAOBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Rat)
University of Lausanne

Curated by ChEMBL
LigandPNGBDBM76662(7-Benzyloxy-4-methyl-chromen-2-one | 4-methyl-7-ph...)
Affinity DataIC50: 18.2nMAssay Description:Inhibition of rat brain MAOBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Siberian Branch of The Russian Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM76662(7-Benzyloxy-4-methyl-chromen-2-one | 4-methyl-7-ph...)
Affinity DataIC50: 5.28E+3nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-(5,6 FAM-AAC GTC AGG GTC TTC C-BHQ1)-3' as substrate measured every 1 min by fluorescence an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/15/2018
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of The Western Cape

Curated by ChEMBL
LigandPNGBDBM76662(7-Benzyloxy-4-methyl-chromen-2-one | 4-methyl-7-ph...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured after 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
University of The Western Cape

Curated by ChEMBL
LigandPNGBDBM76662(7-Benzyloxy-4-methyl-chromen-2-one | 4-methyl-7-ph...)
Affinity DataIC50: 2.62E+3nMAssay Description:Inhibition of recombinant human MAO-A assessed as reduction in 4-hydroxyquinolone production using kynuramine as substrate after 20 mins by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
University of Geneva

Curated by ChEMBL
LigandPNGBDBM76662(7-Benzyloxy-4-methyl-chromen-2-one | 4-methyl-7-ph...)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human MAO-B assessed as reduction in 4-hydroxyquinolone production using kynuramine as substrate after 20 mins by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed
TargetCholinesterase(Horse)
University of The Western Cape

Curated by ChEMBL
LigandPNGBDBM76662(7-Benzyloxy-4-methyl-chromen-2-one | 4-methyl-7-ph...)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of equine serum BuChE using S-butylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/4/2020
Entry Details Article
PubMed