BDBM7649 2,4-bisanilinopyrimidine deriv. 9::4-({4-[(2-fluoro-5-methylphenyl)amino]pyrimidin-2-yl}amino)benzene-1-sulfonamide

SMILES Cc1ccc(F)c(Nc2ccnc(Nc3ccc(cc3)S(N)(=O)=O)n2)c1

InChI Key InChIKey=AZHXFKCTCUPFGL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 7649   

LigandPNGBDBM7649(4-({4-[(2-fluoro-5-methylphenyl)amino]pyrimidin-2-...)
Affinity DataIC50: 6nMpH: 7.0 T: 2°CAssay Description:The kinase activity was assayed using an in vitro scintillation proximity assay (SPA) for measuring incorporation of [gamma-33P] ATP into GST-Rb.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2006
Entry Details Article
PubMed
LigandPNGBDBM7649(4-({4-[(2-fluoro-5-methylphenyl)amino]pyrimidin-2-...)
Affinity DataIC50: 2.70E+3nMpH: 7.0 T: 2°CAssay Description:The kinase activity was assayed using an in vitro scintillation proximity assay (SPA) for measuring incorporation of [gamma-33P] ATP into GST-Rb.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2006
Entry Details Article
PubMed
LigandPNGBDBM7649(4-({4-[(2-fluoro-5-methylphenyl)amino]pyrimidin-2-...)
Affinity DataIC50: 6nMAssay Description:Inhibition of CDK2/Cyclin E (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2017
Entry Details Article
PubMed