BDBM764655 N-[[1-[(4-hydroxy-3,3-dimethylpiperidin-1-yl)methyl]::US20250257057, Example 58

SMILES CC1(C)CN(CC2(CNC(=O)c3cc4c(s3)CCCCCC4)CCC2)CCC1O

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 764655   

TargetCX3C chemokine receptor 1(Rat)
University of Texas System

US Patent
LigandPNGBDBM764655(N-[[1-[(4-hydroxy-3,3-dimethylpiperidin-1-yl)methy...)
Affinity DataEC50:  16.8nMAssay Description:Compounds (as well as stereoisomer(s) thereof and/or salt(s) thereof) were tested for CX3CR1 agonism in a cell based assay with fluorescent readout i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent

TargetCX3C chemokine receptor 1(Mouse)
University of Texas System

US Patent
LigandPNGBDBM764655(N-[[1-[(4-hydroxy-3,3-dimethylpiperidin-1-yl)methy...)
Affinity DataEC50:  19.1nMAssay Description:Compounds (as well as stereoisomer(s) thereof and/or salt(s) thereof) were tested for CX3CR1 agonism in a cell based assay with fluorescent readout i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent

TargetCX3C chemokine receptor 1(Human)
University of Texas System

US Patent
LigandPNGBDBM764655(N-[[1-[(4-hydroxy-3,3-dimethylpiperidin-1-yl)methy...)
Affinity DataEC50:  21.9nMAssay Description:Compounds (as well as stereoisomer(s) thereof and/or salt(s) thereof) were tested for CX3CR1 agonism in a cell based assay with fluorescent readout i...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/24/2025
Entry Details
US Patent