BDBM7621 2,4-bis anilino pyrimidine deriv. 17::3-[(2,5-dichlorophenyl)[2-({4-[3-(dimethylamino)-2-hydroxypropoxy]phenyl}amino)pyrimidin-4-yl]amino]propanenitrile

SMILES CN(C)CC(O)COc1ccc(Nc2nccc(n2)N(CCC#N)c2cc(Cl)ccc2Cl)cc1

InChI Key InChIKey=HUUHWIKDYLSDJJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 7621   

LigandPNGBDBM7621(3-[(2,5-dichlorophenyl)[2-({4-[3-(dimethylamino)-2...)
Affinity DataIC50: 300nMAssay Description:The kinase activity was assayed using an in vitro scintillation proximity assay (SPA) for measuring incorporation of [gamma-33P] ATP into GST-Rb.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2006
Entry Details Article
PubMed
LigandPNGBDBM7621(3-[(2,5-dichlorophenyl)[2-({4-[3-(dimethylamino)-2...)
Affinity DataIC50: 3.00E+3nMAssay Description:The kinase activity was assayed using an in vitro scintillation proximity assay (SPA) for measuring incorporation of [gamma-33P] ATP into GST-Rb.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2006
Entry Details Article
PubMed