BDBM761355 N-[4-(3-Cyanophenyl)-5-(1H-pyrrolo[2,3-b]pyridin-4-yl)thiazol-2-yl]-2-oxa-6-azaspiro[3.3]heptane-6-carboxamide::US20250243194, Example 2.4

SMILES N#Cc1cccc(-c2nc(NC(=O)N3CC4(COC4)C3)sc2-c2ccnc3[nH]ccc23)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 761355   

TargetAdenosine receptor A2b(Human)
Adorx Therapeutics

US Patent
LigandPNGBDBM761355(N-[4-(3-Cyanophenyl)-5-(1H-pyrrolo[2,3-b]pyridin-4...)
Affinity DataKi:  0.5nMAssay Description:All FRET binding experiments were conducted at room temperature in white 384-well plates, in assay binding buffer containing 1× LabMed (Cisbio, Franc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/12/2025
Entry Details
US Patent

TargetAdenosine receptor A1(Human)
Adorx Therapeutics

US Patent
LigandPNGBDBM761355(N-[4-(3-Cyanophenyl)-5-(1H-pyrrolo[2,3-b]pyridin-4...)
Affinity DataKi:  1nMAssay Description:All FRET binding experiments were conducted at room temperature in white 384-well plates, in assay binding buffer containing 1× LabMed (Cisbio, Franc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/12/2025
Entry Details
US Patent

TargetAdenosine receptor A2a(Human)
Adorx Therapeutics

US Patent
LigandPNGBDBM761355(N-[4-(3-Cyanophenyl)-5-(1H-pyrrolo[2,3-b]pyridin-4...)
Affinity DataKi:  1nMAssay Description:All FRET binding experiments were conducted at room temperature in white 384-well plates, in assay binding buffer containing 1× LabMed (Cisbio, Franc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/12/2025
Entry Details
US Patent

TargetAdenosine receptor A3(Human)
Adorx Therapeutics

US Patent
LigandPNGBDBM761355(N-[4-(3-Cyanophenyl)-5-(1H-pyrrolo[2,3-b]pyridin-4...)
Affinity DataKi:  290nMAssay Description:All FRET binding experiments were conducted at room temperature in white 384-well plates, in assay binding buffer containing 1× LabMed (Cisbio, Franc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
11/12/2025
Entry Details
US Patent