BDBM7552 BAY 59-7939 Analog 11::US8822458, 17

SMILES Clc1ccc(s1)C(=O)NC[C@H]1CN(C(=O)O1)c1ccc(cc1)N1CCCC1=O

InChI Key InChIKey=CWYUNIAGLBIPIP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 7552   

TargetCoagulation factor X(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM7552(BAY 59-7939 Analog 11 | US8822458, 17)
Affinity DataIC50: 4nMT: 2°CAssay Description:The enzymatic activity of human factor Xa (FXa) was measured using the conversion of a chromogenic substrate specific for FXa. Factor Xa cleaves p-ni...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2015
Entry Details
Go to US Patent

TargetCoagulation factor X(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM7552(BAY 59-7939 Analog 11 | US8822458, 17)
Affinity DataIC50: 4nMpH: 8.3 T: 2°CAssay Description:The enzymatic activity was measured using chromogenic or fluorogenic substrates in 96-well microtiter plates.Color change was monitored continuously ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/9/2007
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM7552(BAY 59-7939 Analog 11 | US8822458, 17)
Affinity DataIC50: 4nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMed