BDBM755070 Synthesis of (R,13E,14E)-31,7-dimethyl-17-(methylamino)-31H-5,8-dioxa-2-aza-1(5,3),3(4,6)-dipyrazolo [1,5-a]pyrimidinacyclononaphan-9-one ::US20250213571, Compound 4

SMILES CNc1cc2nc3c(cnn13)C(=O)O[C@H](C)COCc1cc(c3nnn(C)c3c1)N2

InChI Key InChIKey=UQESSULXLMKGBL-UHFFFAOYSA-N

Data  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 755070   

LigandPNGBDBM755070(Synthesis of (R,13E,14E)-31,7-dimethyl-17-(methyla...)
Ligand Info
In Depth
Date in BDB:
10/22/2025
Entry Details
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LigandPNGBDBM755070(Synthesis of (R,13E,14E)-31,7-dimethyl-17-(methyla...)
Affinity DataKd: <3.00E+4nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/22/2025
Entry Details
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TargetTyrosine-protein kinase JAK1 [583-855](Human)
Alumis

US Patent
LigandPNGBDBM755070(Synthesis of (R,13E,14E)-31,7-dimethyl-17-(methyla...)
Affinity DataKd:  5.50E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent