BDBM755036 (5S)-8,9-dichloro-7-(2,6-difluoro-3-hydroxy-phenyl)-5-methyl-5H-pyrimido[1,2-a][1,4]benzodiazepin-3-one::US12344614, Example 18

SMILES C[C@@H]1N=C(c2c(F)ccc(O)c2F)c2c(ccc(Cl)c2Cl)-n2ccc(=O)nc21

InChI Key InChIKey=LUUMGXGNVMPSEU-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 755036   

LigandPNGBDBM755036((5S)-8,9-dichloro-7-(2,6-difluoro-3-hydroxy-phenyl...)
Affinity DataKi:  1.30nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

LigandPNGBDBM755036((5S)-8,9-dichloro-7-(2,6-difluoro-3-hydroxy-phenyl...)
Affinity DataKi:  6.60nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent

LigandPNGBDBM755036((5S)-8,9-dichloro-7-(2,6-difluoro-3-hydroxy-phenyl...)
Affinity DataKi:  255nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
10/22/2025
Entry Details
Go to US Patent