BDBM752403 US20250197405, Compound 3

SMILES Cc1ccc(O)c(C)c1-n1c(N)c(C(N)=O)c2c(=O)n(C)c(C)cc21

InChI Key InChIKey=JJZKSUXAXCYGSW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 752403   

LigandChemical structure of BindingDB Monomer ID 752403BDBM752403(US20250197405, Compound 3)
Affinity DataIC50: 11.9nMAssay Description:Compound serial dilution was performed by Echo, and the final concentrations varied from 10 μM to 0.5 nM. 5 μL/well of Enzyme solution was added to t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 752403BDBM752403(US20250197405, Compound 3)
Affinity DataIC50: 12nMAssay Description:Binding affinity to recombinant human PKMYT1 incubated for15 mins by HTRF assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetCyclin-dependent kinase 1(Human)
Insilico Medicine Shanghai Ltd

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 752403BDBM752403(US20250197405, Compound 3)
Affinity DataIC50: 9.14E+3nMAssay Description:Inhibition of CDK1 phosphorylation in human HCC1569 cells incubated for 6 hrs by In-cell Western assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed