BDBM751734 6-[3-(1-methylpyrazol-3-yl)phenyl]-2-morpholino-5-oxazol-2-yl-N-(4-pyridyl)pyrimidin-4-amine ::US20250197375, Compound 74

SMILES Cn1ccc(-c2cccc(-c3nc(N4CCOCC4)nc(Nc4ccncc4)c3-c3ncco3)c2)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 751734   

LigandPNGBDBM751734(6-[3-(1-methylpyrazol-3-yl)phenyl]-2-morpholino-5-...)
Affinity DataIC50: 55nMAssay Description:PIKfyve Biochemical Assay. The biochemical PIKFyve inhibition assays were run by Cama Biosciences according to proprietary methodology based on the P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

LigandPNGBDBM751734(6-[3-(1-methylpyrazol-3-yl)phenyl]-2-morpholino-5-...)
Affinity DataIC50: 550nMAssay Description:Genetic or pharmacological disruption of PIKfyve activity results in enlargement of endosomal vesicles. This enlargement was utilized as a surrogate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent