BDBM751709 9-(1-methyl-1H-pyrazol-3-yl)-2-morpholino-N-(pyridin-4-yl)-6H-isochromeno[4,3-d]pyrimidin-4-amine ::US20250197375, Compound 49

SMILES Cn1ccc(-c2ccc3c(c2)-c2nc(N4CCOCC4)nc(Nc4ccncc4)c2OC3)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 751709   

LigandPNGBDBM751709(9-(1-methyl-1H-pyrazol-3-yl)-2-morpholino-N-(pyrid...)
Affinity DataIC50: 55nMAssay Description:PIKfyve Biochemical Assay. The biochemical PIKFyve inhibition assays were run by Cama Biosciences according to proprietary methodology based on the P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

LigandPNGBDBM751709(9-(1-methyl-1H-pyrazol-3-yl)-2-morpholino-N-(pyrid...)
Affinity DataIC50: 550nMAssay Description:Genetic or pharmacological disruption of PIKfyve activity results in enlargement of endosomal vesicles. This enlargement was utilized as a surrogate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent