BDBM751675 4-(3-(5-methoxy-2-morpholino-6-(pyridin-4-ylamino)pyrimidin-4-yl)phenyl)-1-methylpiperazin-2-one ::US20250197375, Compound 15

SMILES COc1c(Nc2ccncc2)nc(N2CCOCC2)nc1-c1cccc(N2CCN(C)C(=O)C2)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 751675   

LigandPNGBDBM751675(4-(3-(5-methoxy-2-morpholino-6-(pyridin-4-ylamino)...)
Affinity DataIC50: 55nMAssay Description:PIKfyve Biochemical Assay. The biochemical PIKFyve inhibition assays were run by Cama Biosciences according to proprietary methodology based on the P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

LigandPNGBDBM751675(4-(3-(5-methoxy-2-morpholino-6-(pyridin-4-ylamino)...)
Affinity DataIC50: 550nMAssay Description:Genetic or pharmacological disruption of PIKfyve activity results in enlargement of endosomal vesicles. This enlargement was utilized as a surrogate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent