BDBM751667 5-methoxy-6-(5-(1-methyl-1H-pyrazol-3-yl)pyridin-3-yl)-2-morpholino-N-(pyridin-4-yl)pyrimidin-4-amine ::US20250197375, Compound 7
SMILES COc1c(Nc2ccncc2)nc(N2CCOCC2)nc1-c1cncc(-c2ccn(C)n2)c1
InChI Key
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 751667
Target1-phosphatidylinositol 3-phosphate 5-kinase [1-2098,S696N,L932L,Q995L,T998S,S1033A,Q1183K](Human)
Kineta
US Patent
Kineta
US Patent
Affinity DataIC50: 10nMAssay Description:PIKfyve Biochemical Assay. The biochemical PIKFyve inhibition assays were run by Cama Biosciences according to proprietary methodology based on the P...More data for this Ligand-Target Pair
Target1-phosphatidylinositol 3-phosphate 5-kinase [S696N,L932S,Q995L,T998S,S1033A,Q1183K]/Early endosome antigen 1(Human)
Kineta
US Patent
Kineta
US Patent
Affinity DataIC50: 55nMAssay Description:Genetic or pharmacological disruption of PIKfyve activity results in enlargement of endosomal vesicles. This enlargement was utilized as a surrogate ...More data for this Ligand-Target Pair
