BDBM751661 5-methoxy-2-morpholino-N-phenyl-6-(1-phenyl-1H-pyrazol-3-yl)pyrimidine-4-carboxamide ::US20250197375, Compound 1

SMILES COc1c(C(=O)Nc2ccccc2)nc(N2CCOCC2)nc1-c1ccn(-c2ccccc2)n1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 751661   

LigandPNGBDBM751661(5-methoxy-2-morpholino-N-phenyl-6-(1-phenyl-1H-pyr...)
Affinity DataIC50: 55nMAssay Description:PIKfyve Biochemical Assay. The biochemical PIKFyve inhibition assays were run by Cama Biosciences according to proprietary methodology based on the P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

LigandPNGBDBM751661(5-methoxy-2-morpholino-N-phenyl-6-(1-phenyl-1H-pyr...)
Affinity DataIC50: 5.50E+3nMAssay Description:Genetic or pharmacological disruption of PIKfyve activity results in enlargement of endosomal vesicles. This enlargement was utilized as a surrogate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent