BDBM751169 US20250195521, Example A61

SMILES CCn1c(-c2cccnc2[C@H](C)OC)c2c3cc(ccc31)-c1cccc(c1)C[C@H](NC(=O)[C@H](C(C)C)N(C)C(C)=O)C(=O)N1CCC[C@H](N1)C(=O)OCC(C)(C)C2

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 751169   

TargetGTPase KRas [Q61H](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 751169BDBM751169(US20250195521, Example A61)
Affinity DataIC50: 550nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetPeptidyl-prolyl cis-trans isomerase A(Human)
Revolution Medicines, Inc.

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 751169BDBM751169(US20250195521, Example A61)
Affinity DataKd:  1.15E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetGTPase NRas [Q61R](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 751169BDBM751169(US20250195521, Example A61)
Affinity DataIC50: 5.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetGTPase NRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 751169BDBM751169(US20250195521, Example A61)
Affinity DataIC50: 5.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetGTPase NRas(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 751169BDBM751169(US20250195521, Example A61)
Affinity DataIC50: 5.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetGTPase KRas(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 751169BDBM751169(US20250195521, Example A61)
Affinity DataIC50: 5.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

Targetkras g13d(Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 751169BDBM751169(US20250195521, Example A61)
Affinity DataIC50: 5.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetGTPase KRas [G12V](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 751169BDBM751169(US20250195521, Example A61)
Affinity DataIC50: 5.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetGTPase KRas [G13C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 751169BDBM751169(US20250195521, Example A61)
Affinity DataIC50: 5.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetGTPase NRas [Q61K](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 751169BDBM751169(US20250195521, Example A61)
Affinity DataIC50: 5.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetGTPase KRas [G12V](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 751169BDBM751169(US20250195521, Example A61)
Affinity DataIC50: 5.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetGTPase KRas [G12C](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 751169BDBM751169(US20250195521, Example A61)
Affinity DataIC50: 5.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent

TargetGTPase KRas [G12D](Human)
Revolution Medicines

US Patent
LigandChemical structure of BindingDB Monomer ID 751169BDBM751169(US20250195521, Example A61)
Affinity DataIC50: 1.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/14/2025
Entry Details
US Patent