BDBM747837 US12325701, Example 65.

SMILES CN1C[C@H](Cc2ccc(Cl)cc2)N(C2CCN(c3ccccn3)CC2)C[C@@H]1C1CCCC1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 747837   

TargetChitinase-3-like protein 1(Human)
Molecure

Curated by ChEMBL
LigandPNGBDBM747837(US12325701, Example 65.)
Affinity DataIC50: 34nMAssay Description:Displacement of biotinylated HSIII from human His-tagged CHI3L1 (1 to 383 residues) expressed in HEK293F cells by competitive AlphaScreen assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetChitinase-3-like protein 1(Human)
Molecure

Curated by ChEMBL
LigandPNGBDBM747837(US12325701, Example 65.)
Affinity DataIC50: 194nMAssay Description:Displacement of biotinylated ((2R,5S)-5-(4-chlorobenzyl)-4-(1-(pyridin-2-yl)piperidin-4-yl)morpholin-2-yl)methyl 41-oxo-45-((3aS,4S,6aR)-2-oxohexahyd...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetChitinase-3-like protein 1(Human)
Molecure

Curated by ChEMBL
LigandPNGBDBM747837(US12325701, Example 65.)
Affinity DataIC50: 550nMAssay Description:The standard experimental protocol for YKL-40 indirect binding AlphaScreen assay comprised of 5 step additions to wells of a 96 well plate: (i) in th...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In Depth
Date in BDB:
10/4/2025
Entry Details
US Patent