BDBM74685 2-amino-4-phenyl-6-sulfanylidene-1H-pyridine-3,5-dicarbonitrile::2-amino-4-phenyl-6-thioxo-1H-pyridine-3,5-dicarbonitrile::2-azanyl-4-phenyl-6-sulfanylidene-1H-pyridine-3,5-dicarbonitrile::CHEMBL1215100::MLS000105852::SMR000102827::cid_780902

SMILES Nc1[nH]c(=S)c(C#N)c(-c2ccccc2)c1C#N

InChI Key InChIKey=KTPFGSXXUDJFFQ-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 74685   

TargetImportin subunit alpha-1(Human)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM74685(MLS000105852 | CHEMBL1215100 | 2-azanyl-4-phenyl-6...)
Affinity DataEC50: >5.00E+5nMAssay Description:Keywords: Counterscreen, FRET assay, HTS, YIC probe, Dose response, Assay Overview: This is a fluorescence resonance energy transfer (FRET)-based b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/31/2011
Entry Details
PCBioAssay
TargetAcetylcholinesterase(Electric eel)
Laboratorio De Radicales Libres Y QuíMica Computacional (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM74685(MLS000105852 | CHEMBL1215100 | 2-azanyl-4-phenyl-6...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of Electrophorus electricus AChE after 10 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Laboratorio De Radicales Libres Y QuíMica Computacional (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM74685(MLS000105852 | CHEMBL1215100 | 2-azanyl-4-phenyl-6...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of equine serum BuChE after 10 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2011
Entry Details Article
PubMed