BDBM746694 (2R,3R,4S,5R,6R)-2-(hydroxymethyl)-5-methoxy-6-((5-(1-(pyrrolidin-1-ylsulfonyl)piperidin-4-yl)isoxazol-3-yl)methyl)-4-(4-(3,4,5-trifluorophenyl)-1H-1,2,3-triazol-1-yl)tetrahydro-2H-pyran-3-ol::US12319672, Example 3.64

SMILES CO[C@@H]1[C@@H](n2cc(-c3cc(F)c(F)c(F)c3)nn2)[C@@H](O)[C@@H](CO)O[C@@H]1Cc1cc(C2CCN(S(=O)(=O)N3CCCC3)CC2)on1

InChI Key InChIKey=IDSISQZXCXWOJN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 746694   

TargetGalectin-3(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM746694((2R,3R,4S,5R,6R)-2-(hydroxymethyl)-5-methoxy-6-((5...)
Affinity DataIC50: 25nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/25/2025
Entry Details
Go to US Patent

TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM746694((2R,3R,4S,5R,6R)-2-(hydroxymethyl)-5-methoxy-6-((5...)
Affinity DataIC50: 760nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/25/2025
Entry Details
Go to US Patent