BDBM746657 4-(3-(((2R,3R,4R,5R,6R)-3,5-dihydroxy-6-(hydroxymethyl)-4-(4-(3,4,5-trifluorophenyl)-1H-1,2,3-triazol-1-yl)tetrahydro-2H-pyran-2-yl)methyl)isoxazol-5-yl)-N-ethylpiperidine-1-carboxamide::4-(3-(((2R,3R,4R,5R,6R)-3,5-dihydroxy-6-(hydroxymethyl)-4-(4-(3,4,5-trifluorophenyl)-1H-1,2,3-triazol-1-yl)tetrahydro-2H-pyran-2-yl)methyl)isoxazol-5-yl)-N-ethylpiperidine-1-carboxamide [1-(1,3-di-deoxy-3-[4-(3,4,5-trifluorophenyl)-1H-1,2,3-triazol-1-yl]-alpha-D-galacto-pyranose)-1-(5-((1-ethylamino-carbonyl)piperidin-4-yl)-1H-isoxazol-3-yl)-methane]::US12319672, Example 3.27

SMILES CCNC(=O)N1CCC(c2cc(C[C@H]3O[C@H](CO)[C@H](O)[C@H](n4cc(-c5cc(F)c(F)c(F)c5)nn4)[C@H]3O)no2)CC1

InChI Key InChIKey=XNEYMPDVDSTRII-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 746657   

TargetGalectin-3(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM746657(4-(3-(((2R,3R,4R,5R,6R)-3,5-dihydroxy-6-(hydroxyme...)
Affinity DataIC50: 32nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/25/2025
Entry Details
Go to US Patent

TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM746657(4-(3-(((2R,3R,4R,5R,6R)-3,5-dihydroxy-6-(hydroxyme...)
Affinity DataIC50: 870nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/25/2025
Entry Details
Go to US Patent