BDBM746470 (2R,3R,4S,5R,6R)-4-(4-(2,3-difluoro-4-methylphenyl)-1H-1,2,3-triazol-1-yl)-2-(hydroxymethyl)-5-methoxy-6-((3-(1-methylcyclopropyl)isoxazol-5-yl)methyl)tetrahydro-2H-pyran-3-ol::US12319672, Example 1.255

SMILES CO[C@@H]1[C@@H](n2cc(-c3ccc(C)c(F)c3F)nn2)[C@@H](O)[C@@H](CO)O[C@@H]1Cc1cc(C2(C)CC2)no1

InChI Key InChIKey=ILSVRYCCWYOYGX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 746470   

TargetGalectin-3(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM746470((2R,3R,4S,5R,6R)-4-(4-(2,3-difluoro-4-methylphenyl...)
Affinity DataIC50: 32nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/25/2025
Entry Details
Go to US Patent

TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM746470((2R,3R,4S,5R,6R)-4-(4-(2,3-difluoro-4-methylphenyl...)
Affinity DataIC50: 2.06E+3nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/25/2025
Entry Details
Go to US Patent