BDBM746434 1-(4-(3-(((2R,3R,4S,5R,6R)-4-(4-(3-chloro-4,5-difluorophenyl)-1H-1,2,3-triazol-1-yl)-5-hydroxy-6-(hydroxymethyl)-3-methoxytetrahydro-2H-pyran-2-yl)methyl)isoxazol-5-yl)piperidin-1-yl)ethan-1-one::US12319672, Example 1.219

SMILES CO[C@@H]1[C@@H](n2cc(-c3cc(F)c(F)c(Cl)c3)nn2)[C@@H](O)[C@@H](CO)O[C@@H]1Cc1cc(C2CCN(C(C)=O)CC2)on1

InChI Key InChIKey=LFMTXFSAJRNFQI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 746434   

TargetGalectin-3(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM746434(1-(4-(3-(((2R,3R,4S,5R,6R)-4-(4-(3-chloro-4,5-difl...)
Affinity DataIC50: 23nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/25/2025
Entry Details
Go to US Patent

TargetGalectin-1(Human)
Idorsia Pharmaceuticals

US Patent
LigandPNGBDBM746434(1-(4-(3-(((2R,3R,4S,5R,6R)-4-(4-(3-chloro-4,5-difl...)
Affinity DataIC50: 430nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/25/2025
Entry Details
Go to US Patent