BDBM746143 (1S,5R)-3-[1-[1-(1- bicyclo[1.1.1]pentanyl)pyrazol-4- yl]-5-chloro-indazol-6-yl]-8-(2- methyl-3-pyridyl)-3- azabicyclo[3.2.1]octan-8-ol::US12319671, Example 6.71

SMILES Cc1ncccc1C1(O)[C@@H]2CC[C@H]1CN(c1cc3c(cnn3-c3cnn(C45CC(C4)C5)c3)cc1Cl)C2

InChI Key InChIKey=KKINZDCTYKBCJJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 746143   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM746143((1S,5R)-3-[1-[1-(1- bicyclo[1.1.1]pentanyl)pyrazol...)
Affinity DataIC50: 411nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/25/2025
Entry Details
Go to US Patent