BDBM746071 5-chloro-1-[1-(4- cyclopropyl-5- fluoropyrimidin-2- yl)-1H-pyrazol-4- yl]-6-[4-(3- methyloxetan-3- yl)piperazin-1-yl]- 1H-indazole::US12319671, Example 5.24

SMILES CC1(N2CCN(c3cc4c(cnn4-c4cnn(-c5ncc(F)c(C6CC6)n5)c4)cc3Cl)CC2)COC1

InChI Key InChIKey=XUBZDWKOVUBCNZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 746071   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM746071(5-chloro-1-[1-(4- cyclopropyl-5- fluoropyrimidin-2...)
Affinity DataIC50: 625nMMore data for this Ligand-Target Pair
Ligand Info
In Depth
Date in BDB:
9/25/2025
Entry Details
Go to US Patent